Big Data Science is transforming the biomedical research landscape
In 1967, when nuclear physicist Alvin Weinberg1 coined the term Big Science, he was most interested in launching a concentrated effort to develop nuclear technologies. But he anticipated that large-...
Jun, 12, 2017
How data about genes, physical activity, and the environment are yielding insights about obesity
Despite extensive efforts, a clear understanding of the obesity epidemic remains elusive. Scientists have implicated specific causal genes (40 to 60 percent of obesity is considered heritable);...
Nov, 17, 2017
Protein design ascends to new heights
Scientists are now able to design, in principle, almost any protein they want—a feat that was inconceivable just a few years ago. They are reengineering existing proteins found in nature, as...
Nov, 16, 2017
Armed with electronic health records and insurance claim information, data scientists are trying to predict who’s going to become addicted to opioids—and stop them before it’s too late.
A person who is overdosing on opioids exhibits telltale signs: a limp body, slowed breathing and heart rate, and blueish or purplish fingernails and lips. But millions more who live with an opioid...
Nov, 17, 2017
From cellular responses to drugs, to adverse effects and drug repositioning, systems pharmacology gets the BD2K treatment
Relevant NIH Institutes:NCI, NHLBI, NIDDK, NINDS and all other disease-focused Institutes
The Big Data era in biomedicine offers a grand promise: that by crunching vast quantities of multi-...
Jun, 13, 2017
Cost-effectiveness studies yield answers to the complex question of whether clinical genomics testing has value.
Whole-genome testing has now reached the long-anticipated “$1,000 genome” level; and more targeted genetic panels cost even less. But the costs associated with genomic testing don’t...
Nov, 17, 2017
With enough images and associated data, researchers hone in on more effective ways to diagnose and treat brain disease
Relevant NIH Institutes: NIMH, NINDS, NHLBI, NIA, NIBIB, NIDA, NHGRI, NICHD, and NIAAA
About a year and a half ago, brain imaging researchers at the University of Southern California (USC)...
Jun, 14, 2017
Exceptional computational detective work has the potential to reshape our understanding of when and why diseases strike
Relevant NIH Institutes: NCI, NHLBI, NIAMS, NIA, NINDS, NCATS, and all other disease-focused Institutes
Most people don’t know that they’re sick until they feel, for lack of a...
Jun, 14, 2017
How mobile technology and data science are poised to revolutionize healthcare--with BD2K Centers paving the way
Relevant NIH Institutes: NIMH, NINDS, NHLBI, NIA, NIBIB, NIDA, NHGRI, NICHD, and NIAAA
Having already revolutionized fields ranging from communications to finance, mobile technology and data...
Jun, 14, 2017