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Animating Hypotheses

Animated model offers insights

In addition to illustrating complex biological molecules, animations can sometimes offer insight into how those molecules function.   That’s what happened when Grant Jensen, PhD,...
animation, cryotomography, molecular model
Nov, 01, 2016
The Rise of Cryo-Electron Microscopy

Researchers now have a tool for imaging the structures of biological molecules—and they are reaping the benefits big time.

Structure determines function.   That, at least, is what structural biologists will tell you. And these days they have a powerful new tool—or rather, a vastly improved old one—for...
Mar, 31, 2016
Imaging Collections: How They're Stacking Up

As barriers to massive imaging collections fall, researchers can look at human systems in their entirety rather than in pieces

In the beginning there was the Visible Human. It broke new ground by gathering some 2,000 serial images from a death row inmate’s cadaver, and was the first time researchers had sectioned a...
Jun, 30, 2007
Mutual Information
Mutual information (MI) is defined in information theory as a measure of the dependencies between two random variables. There are many biomedical applications in which it is beneficial to quantify...
Jun, 30, 2007
Computation in the Surgical Suite: Navigating the Brain

Computers help surgeons steer through complex terrain

No surgical specialty has embraced computer technology more rapidly, or benefited more from it, than brain surgery. And with good reason: The brain does not readily yield its internal structure and...
Mar, 01, 2014
3D Radiology—Who Knew It Could Look So Good

3D images help physicians design appropriate interventions.

Images of realistic and colorful 3D human body parts line the hall outside the lab. Blood and muscle look like blood and muscle; bone looks like bone. You almost expect to find human cadavers being...
cardiovascular, radiology, stent, visualization
Aug, 31, 2011
Extinct Sabercat Brought to Life

Using software designed for stress testing in engineering, researchers have modeled an American sabercat's skull in the highest resolution vertebrate animal model to date.

Wildlife biologists can watch a lion stalk its prey, but paleontologists must examine fossils to understand how the extinct saber-toothed cat hunted. Researchers now have modeled an American sabercat...
Dec, 31, 2007
The Top Ten Advances of the Last Decade & The Top Ten Challenges of the Next Decade

A recognition of biocomputing's successes and a prediction of what's to come

The last ten years have seen huge leaps in biomedical computing. We now have new ways to integrate and understand vast quantities of data; the capacity for multi-scale biological modeling; and a...
bioinformatics tools, biomedical computing, CAD, computational modeling, data mining, disease surveillance, dynamic modeling, education, eric jakobsson, function prediction, genetic association, genome annotation, in silico screening, medical informatics, neuromodeling, prosthetics, sequence alignment, structure prediction, systems biology, systems biomedicine, telemedicine, tomography
May, 31, 2005
From Sight to Insight: Visualization tools yield biomedical success stories
They're more than just pretty pictures adorning office walls and presentation slides. Beamed into operating room computer monitors, they're guiding the scalpels of brain surgeons. Dancing...
Jan, 01, 2006
Multiscale Modeling in Biomedical Research

New approaches extend multiscale models to represent cellular mesoscales and bridge from molecular to cellular models

In an era of increasingly comprehensive molecular characterizations of living systems, computation has emerged as a key technology to facilitate integrative understanding of biological mechanisms....
Feb, 19, 2013
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