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Getting It Right: Better Validation Key to Progress in Biomedical Computing

Bringing models closer to reality

When the ill-fated space shuttle Columbia launched on January 16, 2003, a large piece of foam fell off and hit the left wing. Alerted of the impact, NASA engineers used a computer model to predict...
7009, competitions, outsource, self-assessment, validation
Oct, 19, 2012
Profiles in Computer Science Courage Part II: Advice on Taking the Plunge
Words of Advice from the Scientists Featured in Profiles in Computer Science Courage   Find  Your Passion “Not every computer scientist will fall in love with the field like I did,...
Mar, 31, 2011
Dissolving a Viral Capsid

Watching the beginning of the infection process in the longest and biggest virus simulation to date.

After a satellite tobacco necrosis virus particle infects a cell, it sheds the calcium ions that hold the capsid proteins together. Next, the proteins start to repel each other, the capsid swells and...
Jun, 06, 2012
Art of the Heart

 

 

  “The creative scientist studies nature with the rapt gaze of the lover, and is guided as often by aesthetics as by rational considerations in guessing how nature works.”—...
Jan, 01, 2006
Automating Literature Surveillance
Today, if researchers want to study complex relationships among genes, diseases and drugs, they have to hope that human curators have read the scientific literature, extracted the relevant...
Mar, 31, 2016
Digging Deep Into the Tree of Life

The DeepTree exhibit zooms users through evolutionary time

The awe-inspiring journey from the first cell some 3.5 billion years ago to the remarkable diversity of species we see today is now available in a tabletop display called DeepTree. “For the...
Aug, 31, 2013
Jackson Pollock’s Protein Interaction Communities

Plot shows how functional communities in yeast protein interaction networks change in size and nature at different levels of resolution

Splashes of bold color seem to drip down the page, bringing to mind the paintings of Jackson Pollock. Spurred by the beauty of the image she had created, Anna Lewis,* a graduate student studying...
protein interaction networks
Mar, 31, 2011
3D Radiology—Who Knew It Could Look So Good

3D images help physicians design appropriate interventions.

Images of realistic and colorful 3D human body parts line the hall outside the lab. Blood and muscle look like blood and muscle; bone looks like bone. You almost expect to find human cadavers being...
cardiovascular, radiology, stent, visualization
Aug, 31, 2011
Architectural Computation Visualizes Cell Choreography
Several years ago, Jackie Wong, MArch, mentored by Jenny E. Sabin, MArch, an architectural designer and lecturer in the School of Design at the University of Pennsylvania, developed a tool for...
May, 31, 2010
Trajectory Optimization and Physical Realism

How adding jet packs to characters' hands can help optimize animations

An animated human figure seeking the optimal path from point A to point B typically relies on computationally expensive hard constraints that force the trajectories to be physically realistic. But...
Jun, 20, 2013
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