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Evolution and HIV: Using Computational Phylogenetics to Close In On a Killer

The study of HIV evolution is not only critical to fighting the virus; it has also driven advances in the computational tools used to study evolution in general.

When Darwin published On the Origin of Species in 1859, it would be decades before HIV would jump from monkeys to humans and set off a devastating worldwide pandemic. But evolution is at the heart of...
Jun, 30, 2009
An Automated Supertree

A Model for Extracting Literature-based Knowledge

Too much scientific knowledge is buried in published literature. Case in point: The phylogenetic relationships among microbial species are locked into numerous publications about individual species...
Phylogenetics
Nov, 10, 2017
Computing the History of Life: Using New Data and New Models to Tackle Old Puzzles

Where did we come from? Ask a computer.

In 1977, the late Carl Woese, PhD, shook up biology when he published the first tree of life based on genetic sequence data. His team showed that, contrary to popular belief, eukaryotes did not...
Sep, 01, 2013

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