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The Golden Age of Public Databases: Speeding Biomedical Discovery

Public databases impact not only how research is done but what kind of research is done in the first place.

The setting: a scientific conference in January 2008. The speaker, Bruce Ponder, MD, PhD, an oncology professor at Cambridge University, is describing a previously unknown link between a particular...
Oct, 01, 2008
Deep Learning and the Future of 
Biomedical Image Analysis

Applying deep learning to biomedical images has the potential to enable earlier and more accurate disease detection, allow more precisely tailored treatment plans, and ultimately improve patient outcomes.

  Revolutionary technological advances in the areas of autonomous vehicles, speech recognition, cybersecurity, and earthquake prediction all depend on the family of artificial intelligence...
Nov, 17, 2017
Citizen Science

Getting cheap, reliable help from lay workers

In pre-Internet days, people sought expert advice for their purchasing decisions—consulting product ratings in magazines such as Consumer Reports and reading newspaper reviews of local dining...
Jun, 03, 2015
Big (Data) Changes

Avi Ma'ayan hopes for improvements in the evaluation of biomedical academic software development projects 

With the increasing diversity of assays that produce massive quantities of data, experimental labs are becoming more and more dependent on software tools and online databases, as well as...
Nov, 01, 2016
Imaging Collections: How They're Stacking Up

As barriers to massive imaging collections fall, researchers can look at human systems in their entirety rather than in pieces

In the beginning there was the Visible Human. It broke new ground by gathering some 2,000 serial images from a death row inmate’s cadaver, and was the first time researchers had sectioned a...
Jul, 01, 2007
Curating Drugs’ Potential with SWEETLEAD

Resolving conflicts among databases

Pharmaceutical research is notoriously expensive. To find safe and effective drugs cost-effectively, some researchers seek new uses for medications that have already leaped the hurdles of the FDA...
Jun, 18, 2014
Genetic Variants and Ill Health: Scanning 500,000 SNPs Yields Gene-Disease Connections

It's an exhilarating time for genome-wide association studies

For the past few months it seemed you couldn’t open a journal without reading results of a new genome-wide association study. The results kept pouring in: four studies in April showing seven...
Oct, 01, 2007
The Harmonizome

A prototype for integrated datasets

For years now, biocomputational scientists have been talking about the need for better data integration. “People talk a lot about how data are in silos and not connected,” says Avi Ma...
Data integration
Nov, 01, 2016
Privacy and Biomedical Research: Building a Trust Infrastructure

An exploration of data-driven and process-driven approaches to data privacy

Trust. It’s the basis of every patient/physician interaction: Shared personal health information is kept confidential and used only for the patient’s benefit. It’s a tradition that...
de-identification, differential privacy, HIPAA, k-anonymity, l-anonymity, privacy
Jan, 02, 2012
Share and Share Alike: A Proposed Set of Guidelines for Both Data and Software
A pair of challenges increasingly threaten the success of bioinformatics research: convincing biologists to share their data and convincing computational colleagues to share their code. Many of us...
Jul, 01, 2006
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Supported by the Mobilize Center,
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Big Data to Knowledge (BD2K)
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(Grant U54EB020405).

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