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Neurocomputation of Music, Faces and Belly Laughs

Pattern-classifiers interpret fMRI data

Peek inside the skull of a couch potato watching reruns on TV and you’ll see non-stop patterns of blood flow throughout the brain. If you learn to pick out which activity patterns match up with...
Sep, 30, 2010
Biocomputation Startups: Where Does Value Lie?

An opportunity and a challenge

When discussing biocomputation startups, there’s one thing people agree on: These days, they don’t generate much excitement among venture capitalists.   “In the 1990s, there...
Mar, 31, 2007
COMPUTATIONAL DRUG DESIGN: new Tricks for Old Drugs

Computation can speed up the time it takes to find new binding partners for old drugs

When cheap drugs are needed fast, researchers and drug companies are increasingly turning to an interesting short-cut: repurposing existing drugs for new uses. Because drugs exert multiple actions in...
docking, drug design, drug repurposing
Mar, 31, 2011
Computation Competitions Take Off!

Contests involving algorithms for protein structure prediction, natural language processing, and computer-aided disease detection are giving researchers a jolt of adrenalin and moving these fields forward

From all parts of the computational spectrum, researchers are duking it out: They are throwing their algorithms into the ring to see which one will out-perform all others on a particular task....
Jun, 30, 2006
Personalized Cancer Treatment: Seeking Cures Through Computation

Incremental progress and measured successes

Personalized cancer therapy is now a reality. A handful of tumor-classifying tests and targeted drugs are in widespread clinical use; and early attempts are underway to match high-risk cancer...
Califano, cancer, Cancer Genome Atlas, G-DOC, network analysis, systems biology
Jan, 01, 2012
COMPUTATION FOR THE BEDSIDE: Optimizing Patient Care

How some tools are already impacting patients

Medical decision-making is often more art than science, requiring physicians to exercise judgment in the face of complex factual circumstances. But now a few tools offer the opportunity to...
AIDS, bone, kidney transplant
Mar, 31, 2011
BENCH-SIDE COMPUTATION: New Tools to Accelerate Experimental Research

It’s impossible to predict what the hottest new tools will be, but here are a few gems that caught our attention

Many experimental researchers rely on computational tools to push the pace and productivity of laboratory research. It’s impossible to predict what the hottest new tools will be, but this...
protein dynamics, simulation, visual system
Mar, 31, 2011
It Takes a Village: Building the Next Generation of Biomedical Ontologies
Although the notion of ontology has been around since Aristotle, the perceived need to develop ontologies in biomedicine has accelerated in recent years as investigators attempt to make sense of the...
Dec, 31, 2008
Computational Biomechanics: Making Strides Toward Patient Care

Moving from intuition to evidence-based intervention

To understand how muscles contract and joints flex, researchers have dissected cadavers and experimented with animals. They can describe how bones, muscles, and tendons connect in a complicated...
Dec, 31, 2006
Computational Biology Catches the Flu: Modeling the bug, the host, the world
The flu virus is an evolutionary marvel. Teams of experts design an appropriate flu vaccine annually just to keep up with the microbe’s ability to evade the human immune system. Multiple...
Jun, 30, 2006
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