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Big Data Analytics In Biomedical Research

Can the complexities of biology be boiled down to Amazon.com-style recommendations?  The examples here suggest possible pathways to an intelligent healthcare system with big data at its core.

“We have recommendations for you,” announces the website Amazon.com each time a customer signs in.   This mega-retailer analyzes billions of customers’ purchases—nearly $...
Jan, 01, 2012
Data’s Identity Crisis: The Struggle to Name It, Describe It, Find It, and Publish It

How can we make data sharing less daunting in order to address the scientific reproducibility problem?

Biomedical data is undergoing an identity crisis.   “How can that be?” you may ask. It’s data: bits of information stored on servers somewhere; sequences of nucleotides in a...
Mar, 31, 2016
The FAIR Data-Sharing Movement: BD2K Centers Make Headway

The BD2K Centers are propelling the data sharing revolution forward at every level of research

Relevant NIH Institutes:  NHGRI, NIAID, NIBIB, NLM, NIEHS, NIGMS, as well as all disease-focused Institutes including NCI, NHLBI, NIDDK, and NINDS   Science that isn’t reproducible...
Jun, 21, 2017
The BiGG Picture

A virtual metabolic network represents intracellular traffic

It’s hard to imagine a map depicting the daily flow of traffic on water, wheels and foot throughout San Diego—or any large city—over the course of a day. “That map can...
Mar, 31, 2007
The Golden Age of Public Databases: Speeding Biomedical Discovery

Public databases impact not only how research is done but what kind of research is done in the first place.

The setting: a scientific conference in January 2008. The speaker, Bruce Ponder, MD, PhD, an oncology professor at Cambridge University, is describing a previously unknown link between a particular...
Sep, 30, 2008
Engineering the Learning Process

Leveraging Science and Technology for Effective Instruction

There is currently unprecedented interest in the potential of technology to transform learning. This buzz around technology and learning is especially loud in higher education, where pundits,...
Oct, 12, 2015
Machine Learning using Big Data: How Apache Spark Can Help

Cleverly designed software makes applications running in clusters more fault-tolerant

Machine learning is the process of automatically building models from data. In the past two decades, researchers in many fields of study have been generating these models from progressively more data...
Jun, 03, 2015
Clinical Decision Support: Providing Quality Healthcare with Help from a Computer
In a classic cartoon, a physician offers a second opinion from his computer.  The patient looks horrified: How absurd to think that a computer could have better judgment than a human doctor! But...
Dec, 31, 2009
Career Paths

A Seller’s Market for Biomedical Data Science Jobs

Just pondering the current job market for biomedical data scientists is likely to put a smile on the faces of many in the field. “The bottom line is, compared to other disciplines,...
Oct, 07, 2015
Blurring Data for Privacy and Usefulness
Hospitals with research agendas share a common problem: how to use medical records for research while protecting patient privacy. One approach—the data-protection equivalent of blurring the...
Dec, 31, 2008
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